This Standard is to be applied to any structure, system, component, activity, or organization that is essential to the safe, reliable, and efficient performance of a nuclear facility and any activities independent of a facility that may affect performance (e.g., transportation of nuclear materials) of those activities. It is also to be applied to all phases of a nuclear facility life cycle (e.g., siting, design, construction, operation, and decommissioning) and all types of activities (e.g., training, testing, software development or use). This Standard is organized in the following four parts: Part I contains requirements for developing and implementing a Quality Assurance Program for nuclear facility applications. Part II contains additional quality assurance requirements for the planning and conduct of specific work activities under a Quality Assurance Program developed in accordance with Part I. Part III contains guidance for implementing the requirements of Parts I and II. Part IV contains guidance for application of NQA-1 and comparisons of NQA-1 with other quality requirements.