Concerns laboratory tests used to measure the toxic components of the fire effluent from either electrotechnical products or materials used in electrotechnical products. It provides guidance on the use and interpretation of results from such tests. It discusses currently available approaches to toxic hazard assessment consistent with the approach of ISO TC 92 SC 3, as set out in ISO/TR 9122-1 to 9122-6, ISO 13344 and ISO/TS 13571. It also provides guidance on the use of toxic potency data in hazard assessment and on principles which underlie the use of combustibility and toxicological information in hazard assessment. The methods described are applicable to data concerning both the incapacitating effects and the lethal effects of fire effluents. The structure of this technical specification remains essentially the same as the first edition but has been usefully expanded in all areas to further clarify the alignment with ISO/TC 92 Fire Safety and in particular with ISO 13344 and ISO/TS 13571. The main topics have been expanded upon to bring them into alignment with the current philosophy for the use and interpretation of test results. - Formulae are given for the calculation of the fraction of the incapacitating dose for each of the asphyxiants, carbon monoxide and hydrogen cyanide. - Volume fractions that are expected to cause incapacitation (F values) are given for some of the more important irritants. - Equations used to predict death are given. - The hyperventilatory effect of carbon dioxide is discussed. Has the status of a basic safety publication in accordance with IEC Guide 104.